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Home Medicines Heart Failure Verivas 2.5, 1 Strip

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Verivas 2.5, 1 Strip

Name: Verivas 2.5, 1 Strip
Brand: Popular Pharmaceuticals Ltd.
SKU: 144705
Price: 282 BDT
Availability: InStock
Rating: 4.8 (86 reviews)

Popular Pharmaceuticals Ltd.

Generic: Vericiguat

Type: Tablet

Pack Size: 10 Pcs

Tablet

10 Pcs

৳ 300 ৳ 282

Verivas is used to lower the risk of cardiovascular death and heart failure (HF) hospitalization in adults with symptomatic chronic heart failure and an ejection fraction below 45%, particularly after a recent HF hospitalization or a need for outpatient IV diuretics.

Discount Price: ৳ 282

MRP: ৳ 300 6% Off

🎉 Save ৳: 18 in this Product

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Regular Delivery - 12-24 Hours, Dhaka City* Charge Tk.39-59
Regular Delivery - 24-48 Hours, Other Cities* Charge Tk.99-110

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✅ Description:

Vericiguat is a soluble guanylate cyclase (sGC) stimulator, a key enzyme in the nitric oxide (NO) signaling pathway.

NO activates sGC, which increases production of cyclic guanosine monophosphate (cGMP).
cGMP regulates vascular tone, heart muscle contractility, and cardiac remodeling.
In heart failure, impaired NO production and reduced sGC activity worsen myocardial and vascular function.

By directly stimulating sGC—both independently and alongside NO—Vericiguat raises intracellular cGMP levels, promoting smooth muscle relaxation and vasodilation, ultimately improving cardiovascular performance.

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✔️ Overdose

Limited human data available.
Doses up to 10 mg (and even 15 mg in some studies) were generally tolerated.
Overdose may lead to hypotension—treat symptomatically.
Not expected to be removed by hemodialysis due to high protein binding.

✔️ Dosage & Administration

Adults

Starting dose: 2.5 mg orally once daily with food
Titration: Double the dose every 2 weeks, as tolerated
Target dose: 10 mg once daily
Tablets may be crushed and mixed with water if swallowing is difficult.

Geriatric Use

No dose adjustments required.
Clinical data show similar safety and efficacy to younger adults, though some older patients may show increased sensitivity.

Hepatic Impairment

No dose adjustment needed for mild to moderate liver impairment.

Renal Impairment

No dosage change required for eGFR ≥ 15 mL/min/1.73 m² (non-dialysis).
Not studied in patients with eGFR < 15 or those on dialysis.

Pediatric Use

Safety and effectiveness have not been established for children or adolescents.

✔️ Side Effect

Common adverse effects include:

Low blood pressure (hypotension)

Anemia (low red blood cell count)

✔️ Drug Interaction

Contraindicated Combination

Other sGC stimulators: Must not be used with Verivas.

Not Recommended

PDE-5 inhibitors (e.g., sildenafil) due to the risk of excessive hypotension.

With Food

Must be taken with food for optimal absorption (bioavailability ~93%).

✔️ Pregnancy & Lactation

Pregnancy

Contraindicated—may cause fetal harm.

Confirm absence of pregnancy before treatment.

Women of reproductive potential must use effective contraception during treatment and for 1 month after therapy.

Breastfeeding

Unknown if Vericiguat passes into breast milk.

Breastfeeding is not recommended during treatment due to potential serious adverse effects on infants.

✔️ Precautions & Warnings

Avoid in pregnant individuals.
Ensure a pregnancy test before starting treatment in women of reproductive age.
Use reliable contraception during therapy and for one month after stopping the drug.

✔️ Storage:

Store below 30°C, protected from light and moisture.

Keep all medicines out of reach of children.

Frequently Asked Questions (FAQ)

+ Q. What is Verivas 2.5 Tablet used for?

Verivas 2.5 Tablet is prescribed to reduce the risk of cardiovascular death and hospitalizations in adults with chronic heart failure, particularly those who have recently been hospitalized or require IV diuretics.

+ Q. What is included in a heart-healthy diet?

Fresh fruits and vegetables Whole grains Lean proteins Adequate water intake Low salt and low saturated fat Limited added sugars

+ Q. What are common symptoms of heart failure?

Watch for: Shortness of breath (especially when lying down) Fatigue Swelling of legs or ankles Irregular heartbeat Rapid weight gain due to fluid retention Nausea or reduced appetite Difficulty concentrating Chest pain (may indicate a heart attack)

+ Q. When and how should I take Verivas 2.5 Tablet?

Take once daily with food, preferably at the same time every day. Consistency improves treatment effectiveness.

+ Q. What lifestyle changes help manage heart failure?

Follow a heart-healthy diet Exercise regularly (as recommended) Maintain a healthy weight Reduce stress Quit smoking Limit alcohol

+ Q. What should I do if I feel dizzy from low blood pressure?

To reduce symptoms of hypotension: Sit or lie down immediately Drink plenty of water Stand up gradually Avoid prolonged standing Avoid heavy lifting and sudden movements

+ Q. Does Verivas 2.5 improve ejection fraction (EF)?

No. Verivas 2.5 helps reduce deaths and hospitalizations and supports heart function, but it does not directly increase EF.

+ Q. Is Verivas 2.5 safe during pregnancy?

No. Verivas 2.5 can harm an unborn baby. Pregnancy must be ruled out before starting the medicine. Effective contraception is required during treatment and for at least one month after stopping it.

+ Q. What is the difference between Verivas 2.5 and Sacubitril + Valsartan?

Both medicines treat heart failure but work differently: Sacubitril + Valsartan contains sacubitril/valsartan. Verivas 2.5 contains Vericiguat, which boosts cGMP levels for improved blood vessel function.

+ Q. Is Verivas 2.5 safe for patients with anemia?

Caution is advised in people with severe anemia. Tell your doctor if you have ever had low red blood cell levels.

+ Q. Can patients with low blood pressure take Verivas 2.5?

Verivas 2.5 may not be suitable for individuals with hypotension. Inform your doctor if you have a history of low blood pressure before starting treatment.

+ Q. Does Verivas 2.5 cause dizziness?

Yes, dizziness or light-headedness is a commonly reported side effect. Resting and avoiding sudden movement can help. If it does not improve, consult your doctor.

+ Q. How does Verivas 2.5 work?

Verivas 2.5 contains Vericiguat, which relaxes and widens the blood vessels. This improves blood flow, reduces the workload on the heart, and helps lower the risk of complications related to heart failure.

+ Q. Can I Verivas 2.5 with erectile dysfunction medicines?

No. Verivas 2.5 should not be taken with sildenafil, tadalafil, or other PDE-5 inhibitors because the combination can cause dangerous drops in blood pressure.

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⚠️Disclaimer:

At ePharma, we’re committed to providing accurate and accessible health information. However, all content is intended for informational purposes only and should not replace medical advice from a qualified physician. Please consult your healthcare provider for personalized guidance. We aim to support, not substitute, the doctor-patient relationship.

📦Pricing Information, Availability:

Product Availability & Pricing Notice Please note that pricing, availability, and service offerings are subject to change due to: Market fluctuations, Manufacturer or supplier adjustments, Product discontinuation or temporary unavailability, Advertising errors. All orders depend on stock availability and staff resources. If services are provided on a time-and-materials basis, any shared estimates are for planning purposes only.